CD9 antibody (CD9) (PE)

Details for Product anti-CD9 Antibody No. ABIN614778, Supplier: Log in to see
Antigen
  • Tspan29
  • BTCC-1
  • DRAP-27
  • MIC3
  • MRP-1
  • TSPAN-29
  • TSPAN29
  • CD9 antigen
  • CD9 antigen-like
  • CD9 molecule
  • Cd9
  • LOC100059512
  • CD9
Alternatives
anti-Mouse (Murine) CD9 antibody for Blocking Reagent
Reactivity
Mouse (Murine)
421
144
75
50
49
46
37
33
24
24
16
12
11
11
11
6
3
2
1
1
1
1
Host
Rat
368
103
84
Clonality (Clone)
Monoclonal ()
Conjugate
This CD9 antibody is conjugated to PE
64
62
38
16
14
13
11
11
11
11
9
8
8
8
8
8
6
5
5
4
4
4
4
2
1
Application
Flow Cytometry (FACS)
458
242
123
73
71
70
56
50
36
34
13
5
5
2
2
2
1
1
1
1
1
1
Options
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Immunogen Permeabilized murine bone marrow-derived mast cells (BMMC)
Clone EM-04
Isotype IgG1
Specificity This antibody recognizes CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Cross-Reactivity (Details) Species reactivity (tested):Mouse
Alternative Name CD9 (CD9 Antibody Abstract)
Background CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
Gene ID 12527
NCBI Accession NP_031683
UniProt P40240
Research Area Embryogenesis, Embryonic stem cells, Reproduction, CD Antigens, Surface Receptors of Immune Cells
Pathways Response to Water Deprivation, Cell-Cell Junction Organization
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE! This product is photosensitive and should be protected from light.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-CD9 antibody (CD9)  (PE) (ABIN614778) anti-CD9 (CD9) antibody (PE)
Background publications Kotha, Zhang, Longhurst, Lu, Jacobs, Cheng, Jennings: "Functional relevance of tetraspanin CD9 in vascular smooth muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia." in: Atherosclerosis, Vol. 203, Issue 2, pp. 377-86, 2009 (PubMed).

Unternaehrer, Chow, Pypaert, Inaba, Mellman: "The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 1, pp. 234-9, 2007 (PubMed).

Liu, Cao, Yang, Li, Hu, Duan: "Tetraspanin CD9 regulates invasion during mouse embryo implantation." in: Journal of molecular endocrinology, Vol. 36, Issue 1, pp. 121-30, 2006 (PubMed).

Le Naour, Rubinstein, Jasmin, Prenant, Boucheix: "Severely reduced female fertility in CD9-deficient mice." in: Science (New York, N.Y.), Vol. 287, Issue 5451, pp. 319-21, 2000 (PubMed).

Schmidt, Künemund, Wintergerst, Schmitz, Schachner: "CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1." in: Journal of neuroscience research, Vol. 43, Issue 1, pp. 12-31, 1996 (PubMed).