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BAG3 antibody (C-Term)
BAG3
Reactivity: Human
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-BAG3 Antibody
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Target
See all BAG3 Antibodies
BAG3
(BCL2-Associated Athanogene 3 (BAG3))
Binding Specificity
All epitopes for BAG3 antibodies
C-Term
Reactivity
All reactivities for BAG3 antibodies
Human
Host
All hosts for BAG3 antibodies
Goat
Clonality
All clonalities for BAG3 antibodies
Polyclonal
Conjugate
All conjugates for BAG3 antibodies
This BAG3 antibody is un-conjugated
Application
All applications for BAG3 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
C-SSMTDTPGNP AAP
Specificity
This antibody detects BAG3 (C-term).
Purification
Immunoaffinity chromatography
Immunogen
Synthetic peptide from C-terminus of human BAG3
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Discover our top product BAG3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for BAG3
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Target
BAG3
(BCL2-Associated Athanogene 3 (BAG3))
Alternative Name
BAG3 (BAG3 Products )
Synonyms
bag3-A antibody, MGC53113 antibody, zgc:100859 antibody, BAG3 antibody, ATBAG3 antibody, BCL-2-associated athanogene 3 antibody, T28J14.160 antibody, T28J14_160 antibody, BAG-3 antibody, BIS antibody, CAIR-1 antibody, MFM6 antibody, AA407278 antibody, Bis antibody, mg638 antibody, BCL2 associated athanogene 3 L homeolog antibody, BCL2-associated athanogene 3 antibody, BCL2 associated athanogene 3 antibody, BCL-2-associated athanogene 3 antibody, Bcl2-associated athanogene 3 antibody, bag3.L antibody, bag3 antibody, BAG3 antibody, Bag3 antibody
Background
This protein has a number of names including Bis, CAIR-1, and BAG-3 and belongs to a family of proteins that share the BAG domain. BAG-3 binds to HSP-70 and inhibits Hsp-mediated proteasomal degradation by virtue of its C-terminal BAG domain that interacts with the ATP binding site of Hsp-70. This protein has also been shown to interact with Bcl-2 and by it self exerts weak anti-apoptotic activity but is synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.Synonyms: BAG family molecular chaperone regulator 3, BAG-3, BIS, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1
Gene ID
9531
NCBI Accession
NP_004272
UniProt
O95817
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