SYT2 antibody (C-Term)

Catalog No. ABIN615616

Product Details anti-SYT2 Antibody

Target: SYT2 (Synaptotagmin II (SYT2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This SYT2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-KPEEEVDALL GKNK

Specificity: Recognizes Synaptotagmin-2 (C-term)

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Bovine.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_796376.2. Genename: SYT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SYT2

Target: SYT2 (Synaptotagmin II (SYT2))

Alternative Name: Synaptotagmin-2 (SYT2 Products)

Synonyms: SytII antibody, RATSYNII antibody, SYNII antibody, R74640 antibody, mKIAA4194 antibody, si:ch211-236j4.1 antibody, synaptotagmin 2 antibody, synaptotagmin II antibody, synaptotagmin IIa antibody, SYT2 antibody, Syt2 antibody, syt2a antibody, syt2 antibody

Background: SYT2 (Synaptotagmin II) belongs to the synaptotagmin family of multi-domained, integral membrane proteins of synaptic vesicles which are thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.Synonyms: SYT-2, SYT2, SYTII, Synaptotagmin 2, Synaptotagmin II

Molecular Weight: 47.2kDa (Mouse NP_033333.2)

Gene ID: 127833

NCBI Accession: NP_796376

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis