TXNDC5 antibody (Internal Region)

Catalog No. ABIN615982

Product Details anti-TXNDC5 Antibody

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Binding Specificity: AA 269-282, Internal Region

Reactivity: Human, Mouse, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This TXNDC5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-RDGKKVDQYK GKRD

Specificity: Recognizes TXNDC5 (269-282). This antibody is expected to recognize both reported isoforms (NP_110437.2, NP_001139021.1) of TXNDC5.

Cross-Reactivity (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_110437.2, NP_001139021.1. Genename: TXNDC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TXNDC5

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Abstract: TXNDC5 Products

Synonyms: ENDOPDI antibody, ERP46 antibody, HCC-2 antibody, PDIA15 antibody, STRF8 antibody, UNQ364 antibody, wu:fb20a07 antibody, wu:fb55b10 antibody, zgc:66265 antibody, AL022641 antibody, ERp46 antibody, PC-TRP antibody, PDIL5-1 antibody, Txndc5 antibody, erp46 antibody, TXNDC5 antibody, MUTED antibody, endopdi antibody, unq364 antibody, thioredoxin domain containing 5 antibody, protein disulfide isomerase antibody, thioredoxin domain containing 5 L homeolog antibody, biogenesis of lysosomal organelles complex 1 subunit 5 antibody, TXNDC5 antibody, txndc5 antibody, Txndc5 antibody, PDIL5-1 antibody, txndc5.L antibody, BLOC1S5 antibody, CC1G_08236 antibody

Background: ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.Synonyms: ERp46, Endoplasmic reticulum resident protein 46, Thioredoxin domain-containing protein 5, Thioredoxin-like protein p46

Gene ID: 81567

NCBI Accession: NP_001139021

UniProt: Q8NBS9

Pathways: Cell RedoxHomeostasis