SUFUH antibody (pSer342)

Catalog No. ABIN616041

Product Details anti-SUFUH Antibody

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Binding Specificity: pSer342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUFUH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: A-P-S(p)-R-K

Specificity: This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide sequence around phosphorylation site of Serine 342 derived from Human Sufu

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Alternative Name: SUFU / SUFUH (SUFUH Products)

Synonyms: CG6054 antibody, Dmel\\CG6054 antibody, SU(FU) antibody, SUFU antibody, Su(Fu) antibody, SuFu antibody, Sufu antibody, su(fu) antibody, sufu antibody, Xsufu antibody, sufuh antibody, sufuxl antibody, PRO1280 antibody, SUFUH antibody, SUFUXL antibody, Su(fu) antibody, dre antibody, fi39e05 antibody, wu:fi39e05 antibody, 2810026F04Rik antibody, b2b273Clo antibody, Suppressor of fused antibody, SUFU negative regulator of hedgehog signaling L homeolog antibody, SUFU negative regulator of hedgehog signaling antibody, suppressor of fused homolog (Drosophila) antibody, Su(fu) antibody, sufu.L antibody, SUFU antibody, sufu antibody, Sufu antibody

Background: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).Synonyms: Suppressor of fused homolog

Molecular Weight: 54 kDa

Gene ID: 51684

NCBI Accession: NP_001171604

UniProt: Q9UMX1

Pathways: Hedgehog Signaling, Tube Formation, Maintenance of Protein Location