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CDC25B antibody (pSer149)

CDC25B Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN616043
  • Target See all CDC25B Antibodies
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Binding Specificity
    • 27
    • 22
    • 18
    • 15
    • 15
    • 11
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer149
    Reactivity
    • 137
    • 105
    • 55
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Mouse, Rat
    Host
    • 185
    • 2
    Rabbit
    Clonality
    • 176
    • 11
    Polyclonal
    Conjugate
    • 72
    • 15
    • 12
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    This CDC25B antibody is un-conjugated
    Application
    • 167
    • 79
    • 52
    • 52
    • 36
    • 30
    • 14
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    F-R-S(p)-L-P
    Specificity
    This antibody detects endogenous level of Cdc25B protein only when phosphorylated at serine 149.
    Cross-Reactivity (Details)
    Species reactivity (tested):Mouse, rat
    Purification
    Affinity-chromatography using epitope-specific peptide
    Immunogen
    Peptide sequence around phosphorylation site of Serine 149 derived from Mouse Cdc25B.
    Top Product
    Discover our top product CDC25B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store (in aliquots) at -20 °C.
  • Target
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Alternative Name
    Cdc25B (CDC25B Products)
    Synonyms
    CDC25B antibody, AI604853 antibody, cell division cycle 25B antibody, cdc25b antibody, CDC25B antibody, Cdc25b antibody
    Background
    Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
    Gene ID
    12531
    NCBI Accession
    NP_001104545
    UniProt
    Q9DBN8
    Pathways
    Cell Division Cycle, M Phase, Autophagy
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