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SEC63 antibody

SEC63 Reactivity: Human, Mouse, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630338
  • Target See all SEC63 Antibodies
    SEC63 (SEC63 Homolog (SEC63))
    Reactivity
    • 27
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Dog
    Host
    • 23
    • 4
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    This SEC63 antibody is un-conjugated
    Application
    • 27
    • 17
    • 14
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    SEC63 antibody was raised using a synthetic peptide corresponding to a region with amino acids WWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRS
    Top Product
    Discover our top product SEC63 Primary Antibody
  • Application Notes
    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    SEC63 Blocking Peptide, catalog no. 33R-10039, is also available for use as a blocking control in assays to test for specificity of this SEC63 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SEC63 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    SEC63 (SEC63 Homolog (SEC63))
    Alternative Name
    SEC63 (SEC63 Products)
    Synonyms
    DNAJC23 antibody, ERdj2 antibody, PRO2507 antibody, SEC63L antibody, 5730478J10Rik antibody, AI649014 antibody, AW319215 antibody, SEC63-like antibody, zgc:92718 antibody, SEC63 homolog, protein translocation regulator antibody, SEC63-like (S. cerevisiae) antibody, SEC63 homolog, protein translocation regulator L homeolog antibody, SEC63 antibody, Sec63 antibody, sec63 antibody, sec63.L antibody
    Background
    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.
    Molecular Weight
    88 kDa (MW of target protein)
    Pathways
    ER-Nucleus Signaling
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