H2AFY2 antibody (Middle Region)
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- Target See all H2AFY2 Antibodies
- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFY2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- H2 AFY2 antibody was raised against the middle region of H2 FY2
- Purification
- Affinity purified
- Immunogen
- H2 AFY2 antibody was raised using the middle region of H2 FY2 corresponding to a region with amino acids PRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRT
- Top Product
- Discover our top product H2AFY2 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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H2AFY2 Blocking Peptide, catalog no. 33R-7327, is also available for use as a blocking control in assays to test for specificity of this H2AFY2 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FY2 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
- Alternative Name
- H2AFY2 (H2AFY2 Products)
- Synonyms
- macroH2A2 antibody, RGD1561371 antibody, MGC69037 antibody, MGC130768 antibody, macroh2a2 antibody, im:6898017 antibody, wu:fa14g05 antibody, zgc:114051 antibody, H2AFY2 antibody, H2A histone family member Y2 antibody, H2A histone family, member Y2 antibody, H2A histone family member Y2 L homeolog antibody, core histone macro-H2A.2 antibody, H2AFY2 antibody, H2afy2 antibody, h2afy2.L antibody, h2afy2 antibody, LOC100224559 antibody, LOC100343925 antibody, LOC100456998 antibody, LOC489024 antibody, LOC100738475 antibody
- Background
- H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
- Molecular Weight
- 40 kDa (MW of target protein)
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