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NSUN2 antibody (C-Term)

NSUN2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630733
  • Target See all NSUN2 Antibodies
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 16
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This NSUN2 antibody is un-conjugated
    Application
    • 23
    • 19
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    NSUN2 antibody was raised against the C terminal of NSUN2
    Purification
    Affinity purified
    Immunogen
    NSUN2 antibody was raised using the C terminal of NSUN2 corresponding to a region with amino acids FINSRIITVSMEDVKILLTQENPFFRKLSSETYSQAKDLAKGSIVLKYEP
    Top Product
    Discover our top product NSUN2 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    NSUN2 Blocking Peptide, catalog no. 33R-2934, is also available for use as a blocking control in assays to test for specificity of this NSUN2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NSUN2 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Alternative Name
    NSUN2 (NSUN2 Products)
    Synonyms
    D13Wsu123e antibody, Misu antibody, MISU antibody, MRT5 antibody, SAKI antibody, TRM4 antibody, RGD1311954 antibody, NOL1/NOP2/Sun domain family member 2 antibody, NOP2/Sun RNA methyltransferase family member 2 antibody, NOP2/Sun RNA methyltransferase family, member 2 antibody, NOP2/Sun RNA methyltransferase family member 2 S homeolog antibody, Nsun2 antibody, NSUN2 antibody, nsun2.S antibody
    Background
    Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA).
    Molecular Weight
    86 kDa (MW of target protein)
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