EDC4 antibody (N-Term)

Catalog No. ABIN632803

Product Details anti-EDC4 Antibody

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDC4 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: EDC4 antibody was raised against the N terminal of EDC4

Purification: Affinity purified

Immunogen: EDC4 antibody was raised using the N terminal of EDC4 corresponding to a region with amino acids LQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPV

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

EDC4 Blocking Peptide, catalog no. 33R-5303, is also available for use as a blocking control in assays to test for specificity of this EDC4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EDC4 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Alternative Name: EDC4 (EDC4 Products)

Synonyms: VARICOSE antibody, ge-1 antibody, hedls antibody, rcd-8 antibody, GE1 antibody, Ge-1 antibody, HEDL5 antibody, HEDLS antibody, RCD-8 antibody, RCD8 antibody, BC022641 antibody, si:ch211-237c7.1 antibody, wu:fe26b05 antibody, LRRG00115 antibody, Nrn1l antibody, RGD1309136 antibody, enhancer of mRNA decapping 4 antibody, Transducin/WD40 repeat-like superfamily protein antibody, enhancer of mRNA decapping 4 L homeolog antibody, EDC4 antibody, VCS antibody, edc4 antibody, Edc4 antibody, edc4.L antibody

Background: In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).

Molecular Weight: 152 kDa (MW of target protein)