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ARC (Middle Region) antibody

Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN632995
  • Target
    ARC
    Binding Specificity
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 33
    • 10
    • 10
    • 3
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 23
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 27
    • 16
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    ARC antibody was raised against the middle region of ARC
    Purification
    Affinity purified
    Immunogen
    ARC antibody was raised using the middle region of ARC corresponding to a region with amino acids ELDLPQKQGEPLDQFLWRKRDLYQTLYVDADEEEIIQYVVGTLQPKLKRF
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    ARC Blocking Peptide, catalog no. 33R-2534, is also available for use as a blocking control in assays to test for specificity of this ARC antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ARC antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    ARC
    Synonyms
    activity regulated cytoskeleton associated protein antibody, Arc antibody
    Background
    ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
    Molecular Weight
    45 kDa (MW of target protein)
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