PSME1 antibody (Middle Region)

Catalog No. ABIN634319

Product Details anti-PSME1 Antibody

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSME1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: PSME1 antibody was raised against the middle region of PSME1

Purification: Affinity purified

Immunogen: PSME1 antibody was raised using the middle region of PSME1 corresponding to a region with amino acids KEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEI

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PSME1 Blocking Peptide, catalog no. 33R-4340, is also available for use as a blocking control in assays to test for specificity of this PSME1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PSME1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PSME1

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Alternative Name: PSME1 (PSME1 Products)

Synonyms: fk89d05 antibody, wu:fk89d05 antibody, IFI5111 antibody, PA28A antibody, PA28alpha antibody, REGalpha antibody, AW413925 antibody, PA28a antibody, proteasome activator subunit 1 antibody, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody, psme1 antibody, PSME1 antibody, Psme1 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.

Molecular Weight: 28 kDa (MW of target protein)

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA