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Antibodies
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anti-Vitamin D Receptor (VDR) antibody
Vitamin D Receptor (VDR) antibody
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| Synonyms |
vdr-A, xVDR, VDR, NR1I1, NR1I1-B, gb:dq017633, vdr-b, Ci-VDR-b, LOC100008907, LOC100136219, LOC100136371, vdr0, vdralpha, vdrbeta, DKFZp469H1213, LOC100221284, Nr1i1 |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN640145 |
| Quantity |
0.1 mg (IgG concentration 0.5 mg/ml) |
| Price |
408.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Characteristics
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Goat Anti-Human Vitamin D Receptor
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Alternative name
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Vitamin D Receptor
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Immunogen
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Peptide sequence CGNQDYKYRVSD corresponding to the internal region of Vitamin D receptor (NP_000367.1).
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Cross-Reactivity
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Rat (Rattus), Mouse (Murine), Dog (Canine)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Synonyms: NR1I1
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Specificity
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DS-PB-02327 recognizes human vitamin D nuclear hormone receptor (VDR) a 48 kDa member of the trans-acting transcriptional regulatory factors. On binding vitamin D, VDR regulates the expression of hormone sensitive genes. The main downstream target of VDR is involved in bone mineral metabolism although VDR is also involved in immune response and cancer metabolic pathways. VDR also acts as a receptor for secondary bile acid lithocholic acid. Additionally, signalling and oncogenic activity of beta-catenin signalling has been shown to be repressed by VDR.
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Concentration
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IgG concentration 0.5 mg/ml
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Purification
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Purified
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Buffer
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TRIS buffered saline pH7.3
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Preservative
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0.02% Sodium Azide (NaN 3 ), 0.5% Bovine Serum Albumin
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Storage
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Store at +4 ° C or at -20 ° C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch
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Research Area
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Cancer, Transcription Factors, Vitamins
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Restrictions
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For Research Use only
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Alternatives for antigen "Vitamin D Receptor (VDR)", type "Antibodies"
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Hosts
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Rabbit (2), Goat (1), Rat (1)
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Reactivities
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Human (3), Bird (Avian) (1), Dog (Canine) (1), Mammalian (1), Mouse (Murine) (1), Rat (Rattus) (1)
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Applications
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Western Blotting (WB) (4), ELISA (2), Immunofluorescence (IF) (2), Functional Studies (Func) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)
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Epitopes
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Ab-208 (1), pSer208 (1)
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