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Antibodies
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anti-Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) antibody
Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) antibody
| Antigen |
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| Synonyms |
AG2, GOB-4, HAG-2, XAG-2, PDIA17, Agr2h, Gob-4, mAG-2, MGC112187, wu:fj29g05, zgc:112187, agr2, AGR2, MGC128276, hag3, hag-3, bcmp11, MGC89004 |
| Clonality |
Monoclonal |
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Host
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Reactivity
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Human (39), Mouse (Murine) (14), Rat (Rattus) (9), Cow (Bovine) (3), Dog (Canine) (3), Chicken (2), Cat (Feline) (1), Horse (Equine) (1), Monkey (1), Orang-Utan (1), Zebrafish (1)
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Conjugate
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Application
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 Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)
Western Blotting (WB) (38), ELISA (32), Immunohistochemistry (IHC) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14), Immunoprecipitation (IP) (3), Immunocytochemistry (ICC) (2), Dot Blot (DB) (1), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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| Catalog no. |
ABIN649264 |
| Quantity |
100ul (Variants) |
| Price |
450.00 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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AGR2
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Gene ID
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10551
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UniProt
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O95994
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Description
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Other names: AGR2, AG2, Anterior gradient protein 2 homolog, Secreted cement gland protein XAG-2 homolog,HPC8
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Characteristics
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Rabbit Monoclonal Antibody
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Specificity
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A synthetic peptide corresponding to residues in human AGR2 was used as an immunogen.
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Molecular Weight
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17 kDA
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Comments
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Background: The anterior gradient protein-2 (AGR2) is a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. It has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells. Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells (1). Specifically, AGR2 may serve as a useful molecular marker and/or potential therapeutic target for hormone-responsive breast tumours (2). AGR2 expression promotes tumor growth in esophageal adenocarcinoma cells and intestinal cells of secretory lineage, suggesting that AGR2 may be important for the growth and development of the intestine as well as esophageal adenocarcinomas (3).
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Application Notes
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The suggested dilution is: WB: ~~ 1:1000 IP: ~~ 1:30 FC: ~~ 1:20 ICC: ~~ 1:100~250 IHC: ~~ 1:250~500
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Buffer
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50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
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AGR2 Antibody can be stored at -20°C for up to 12 months from time of receipt.
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Research Area
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Cell Signaling, Protein Modifications, Cancer, Cell Structure
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Restrictions
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For Research Use only
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Product
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Wang, Hao, Lowe: "The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation." in: Cancer research, Vol. 68, Issue 2, pp. 492-7, 2008 (PubMed).
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Alternatives for antigen "Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2)", type "Antibodies"
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Hosts
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Rabbit (34), Goat (5), Mouse (5), Sheep (1)
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Reactivities
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Human (39), Mouse (Murine) (14), Rat (Rattus) (9), Cow (Bovine) (3), Dog (Canine) (3), Chicken (2), Cat (Feline) (1), Horse (Equine) (1), Monkey (1), Orang-Utan (1), Zebrafish (1)
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Applications
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Western Blotting (WB) (38), ELISA (32), Immunohistochemistry (IHC) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14), Immunoprecipitation (IP) (3), Immunocytochemistry (ICC) (2), Dot Blot (DB) (1), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Biotin (3)
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Epitopes
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N-Term (6), AA 21-175 (3), Internal Region (3), AA 55-72 (2), Center (1)
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2013 BioMed Central Research Awards
