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Details for Product No. ABIN649323

Agouti Signaling Protein (ASIP) antibody

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Antigen
Synonyms AGSW, AGTI, AGTIL, ASP, SHEP9, A, ASIP, As
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Monoclonal
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN649323
Quantity 100 µL
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Specificity A synthetic peptide corresponding to residues near the C-terminus of human ASIP was used as immunogen. This antibody is predicted to detect isoforms 2-7 based on sequence analysis.
Alternative Name ASIP
Background The agouti signaling protein (ASIP) is an adaptor protein involved in asymmetrical cell division and cell polarization processes. ASIP seems to play a central role in the formation of epithelial tight junctions. ASIP may affect the quality of hair pigmentation, and act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone (2-3). ASIP may also play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes (4-5).
Synonyms: PARD3, PAR3, PAR3A, Partitioning defective 3 homolog, CTCL tumor antigen se2-5,PAR3-alpha
Molecular Weight 150 kDA
Gene ID 56288
UniProt Q8TEW0
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes The suggested dilution is: WB: ~~ 1:500 FC: ~~ 1:20
Comment

Background: The agouti signaling protein (ASIP) is an adaptor protein involved in asymmetrical cell division and cell polarization processes. ASIP seems to play a central role in the formation of epithelial tight junctions. ASIP may affect the quality of hair pigmentation, and act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone (2-3). ASIP may also play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes (4-5).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Storage -20 °C
Storage Comment ASIP Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Kwon, Bultman, Löffler et al.: "Molecular structure and chromosomal mapping of the human homolog of the agouti gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 21, pp. 9760-4, 1994 (PubMed).

Alternatives for antigen "Agouti Signaling Protein (ASIP)", type "Antibodies"
Hosts (5)
Reactivities (3), (2)
Applications (3), (3), (2)
Epitopes (2), (2), (1)
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