BCL2-Associated Athanogene 2 (BAG2) antibody
| Antigen |
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| Synonyms |
BAG-2, KIAA0576, MGC149462, dJ417I1.2, BC016230, MGC36682, 2610042A13Rik, MGC64195, zgc:64195, bag2, MGC89300, BAG2, MGC187837, MGC128966 |
| Clonality |
Monoclonal |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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 Alternatives Western Blotting (WB), Immunocytochemistry (ICC)
Western Blotting (WB) (16), Immunofluorescence (IF) (15), ELISA (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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| Catalog no. |
ABIN649345 |
| Quantity |
100ul (Variants) |
| Price |
450.00 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Bag-2
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Gene ID
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9532
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UniProt
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O95816
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Description
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Other names: BAG2, BAG family molecular chaperone regulator 2, Bcl-2-associated athanogene 2
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Characteristics
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Rabbit Monoclonal Antibody
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Specificity
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A synthetic peptide corresponding to residues in the C-terminus of human Bag-2 was used as immunogen.
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Molecular Weight
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23 kDA
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Comments
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Background: BAG-2 is a member of a family of BAG-related proteins (BAG-2, BAG-3, BAG-4, BAG-5). BAG-family proteins may play a role in providing opportunities for specification and diversification of Heat Shock Protein (Hsp70) chaperone functions. Hsp70 family molecular chaperones play critical roles in protein folding and trafficking in all eukaryotic cells. BAG-1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. BAG-2 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (1).
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Application Notes
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The suggested dilution is: WB: ~~ 1:1000~2000 ICC: ~~ 1:100~250
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Buffer
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50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
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Bag-2 Antibody can be stored at -20°C for up to 12 months from time of receipt.
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Research Area
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Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure
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Restrictions
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For Research Use only
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Product
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Takayama, Xie, Reed: "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 781-6, 1999 (PubMed).
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Alternatives for antigen "BCL2-Associated Athanogene 2 (BAG2)", type "Antibodies"
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Hosts
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Rabbit (27), Goat (4), Mouse (1)
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Reactivities
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Human (30), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (19), Dog (Canine) (19), Horse (Equine) (18), Pig (Porcine) (18), Chicken (1), Zebrafish (1)
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Applications
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Western Blotting (WB) (16), Immunofluorescence (IF) (15), ELISA (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (4)
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2013 BioMed Central Research Awards
