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Hepatic Leukemia Factor (HLF) antibody

Details for Product No. ABIN649870
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Antigen
Synonyms E230015K02Rik, HIF-2alpha, HIF2A, HLF, HRF, MOP2, bHLHe73, Hif2a, DKFZp469P0721, Hlf, HLF1, zgc:153035
Reactivity
Human, Rat (Rattus)
(23), (3), (1)
Host
Rabbit
(16), (8)
Clonality
Monoclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (12), (5), (1)
Pubmed 2 references available
Quantity 100 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN649870
392.86 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Specificity A synthetic peptide corresponding to residues near the C-term in human HLF was used as an immunogen.
Alternative Name HLF
Background Hepatic leukemia factor (HLF) is a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors (2). It is a transcription factor related to the CES-2 protein, which controls apoptosis of the NSM serotoninergic neurons (1). HLF has been linked to malignancies of the lymphoid system, but is not normally expressed in these cells. HLF transcripts are detected in the liver, kidney, lung and adult nervous system. It plays a role in the function of differentiated neurons in the adult nervous system (1), and it forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription (2).
Molecular Weight 36 kDA
Gene ID 3131
UniProt Q16534
Research Area Cancer, Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes The suggested dilution is: WB: = 1:500-1000
Comment

Background: Hepatic leukemia factor (HLF) is a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors (2). It is a transcription factor related to the CES-2 protein, which controls apoptosis of the NSM serotoninergic neurons (1). HLF has been linked to malignancies of the lymphoid system, but is not normally expressed in these cells. HLF transcripts are detected in the liver, kidney, lung and adult nervous system. It plays a role in the function of differentiated neurons in the adult nervous system (1), and it forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription (2).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment HLF Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Hitzler, Soares, Drolet et al.: "Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice." in: Brain research, Vol. 820, Issue 1-2, pp. 1-11, 1999 (PubMed).

Pruitt, Tatusova, Maglott: "NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins." in: Nucleic acids research, Vol. 35, Issue Database issue, pp. D61-5, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN649870
392.86 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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