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Heat Shock 27kDa Protein 1 (HSPB1) antibody

Details for Product No. ABIN649891
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Antigen
Synonyms
cb153, cb660, hsp1, hsp25, hsp27, id:ibd2821, sb:cb660, zgc:103437, HSPB1, cmt2f, hs.76067, hsp28, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27, Hs.78846, LOH11CR1K, MKBP, Hsp27, 27kDa, 2810021G ... show more
cb153, cb660, hsp1, hsp25, hsp27, id:ibd2821, sb:cb660, zgc:103437, HSPB1, cmt2f, hs.76067, hsp28, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27, Hs.78846, LOH11CR1K, MKBP, Hsp27, 27kDa, 2810021G24Rik show less
Reactivity
Human
(453), (108), (96), (61), (47), (25), (12), (10), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(341), (136), (2)
Clonality
Monoclonal
Conjugate
Un-conjugated
(19), (19), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(390), (178), (154), (107), (79), (67), (48), (40), (23), (23), (12), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µL
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Catalog No. ABIN649891
450.00 $
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Specificity A synthetic peptide corresponding to residues near the N-terminus of human Hsp 27 was used as an immunogen.
Alternative Name HSP27
Background Heat shock protein (HSP) 27 is one of the small HSPs, and is involved in stress resistance and actin organization. HSP27 is expressed in response to environmental stresses such as heat shock, or estrogen stimulation in MCF-7 cells (1,2). HSP27 is phosphorylated at serines 15, 78 and 82 by MAPKAP kinase 2 as a result of the activation of the p38 MAP kinase pathway (3,4).
Synonyms: HSPB1, HSP27, HSP28, Heat shock protein beta-1, Estrogen-regulated 24 kDa protein,28 kDa heat shock protein
Molecular Weight 27 kDA
Gene ID 3315
UniProt P04792
Research Area Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Neurology, Cell Structure
Application Notes IHC: = 1:100, WB: = 1:1000-10000
Comment

Background: Heat shock protein (HSP) 27 is one of the small HSPs, and is involved in stress resistance and actin organization. HSP27 is expressed in response to environmental stresses such as heat shock, or estrogen stimulation in MCF-7 cells (1,2). HSP27 is phosphorylated at serines 15, 78 and 82 by MAPKAP kinase 2 as a result of the activation of the p38 MAP kinase pathway (3,4).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment HSP27 Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Rouse, Cohen, Trigon et al.: "A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins." in: Cell, Vol. 78, Issue 6, pp. 1027-37, 1994 (PubMed).

Validation Images
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