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IL-6 antibody

Details for Product No. ABIN649924
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Antigen
Synonyms Il-6, ILg6, Ifnb2, BSF2, HGF, HSF, IFNB2, IL-6, CHIL-6, il6
Reactivity
Human
(335), (149), (101), (27), (27), (24), (15), (10), (6), (4), (4), (4), (3), (3), (1), (1)
Host
Rabbit
(276), (160), (93), (18), (7), (3), (1)
Clonality
Monoclonal
Conjugate
Un-conjugated
(68), (25), (14), (9), (9), (9), (9), (9), (9), (9), (9), (9), (4), (2), (1), (1), (1), (1)
Application
Western Blotting (WB)
(339), (329), (87), (75), (74), (61), (57), (38), (37), (36), (35), (24), (18), (16), (15), (13), (12), (10), (10), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µL
Options
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Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN649924
392.86 $
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Specificity A recombinant human IL-6 protein was used as immunogen.
Background Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).
Synonyms: IL6, IFNB2, Interleukin-6, Interferon beta-2,Hybridoma growth factor,CTL differentiation factor
Molecular Weight 22 kDA
Gene ID 3569
UniProt P05231
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes The suggested dilution is: WB: = 1:10000
Comment

Background: Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment IL-6 Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Hirano, Yasukawa, Harada et al.: "Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin." in: Nature, Vol. 324, Issue 6092, pp. 73-6, 1986 (PubMed).

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