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Details for Product No. ABIN649924

IL-6 antibody

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Antigen
Synonyms HGF, HSF, BSF2, IL-6, IFNB2, Il-6, ILg6, Ifnb2, CHIL-6
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN649924
Quantity 100 µL
Price
392.86 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Specificity A recombinant human IL-6 protein was used as immunogen.
Background Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).
Synonyms: IL6, IFNB2, Interleukin-6, Interferon beta-2,Hybridoma growth factor,CTL differentiation factor
Molecular Weight 22 kDA
Gene ID 3569
UniProt P05231
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes The suggested dilution is: WB: ~~ 1:10000
Comment

Background: Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Storage -20 °C
Storage Comment IL-6 Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Hirano, Yasukawa, Harada et al.: "Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin." in: Nature, Vol. 324, Issue 6092, pp. 73-6, 1986 (PubMed).

Alternatives for antigen "IL-6", type "Antibodies"
Hosts (271), (156), (115), (22), (5), (4), (1)
Reactivities (341), (161), (100), (29), (28), (23), (15), (10), (6), (6), (4), (4), (4), (3), (1)
Applications (369), (346), (87), (69), (68), (60), (60), (57), (44), (30), (29), (19), (17), (16), (16), (14), (13), (10), (10), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Conjugates (72), (25), (13), (10), (9), (9), (9), (9), (9), (9), (9), (9), (6), (4), (2), (2), (1), (1), (1)
Epitopes (16), (16), (6), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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