No Products on your Comparison List.
Your basket is empty.
The Independent Validation Initiative strives to provide you with high quality data.
Find out more
Background: Extracellular signal-regulated kinases Erk1 (p44 MAPK) and Erk2 (p42 MAPK) Serine/Threonine protein kinase are part of a subfamily of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth, differentiation, apoptosis and signal transduction (1,2,3). The simultaneous tyrosine/threonine phosphorylation of ERK1 and ERK2 results in their activation. Although ERK1 and ERK2 resemble one another closely in sequence and are activated by similar pathways, they appear to have different tissue distributions (4) and show differential phosphorylation of potential intracellular substrates (5).