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Details for Product No. ABIN650422

KIT Ligand (KITLG) antibody

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Antigen
Synonyms MGF, SCF, FPH2, KL-1, Kitl, SF, SHEP7, Clo, Con, Gb, Kitlg, Mgf, SLF, Sl, blz, contrasted, 710-712, CSF, KITL, Xkl-1, Xsl, Xsl-1, Xsl-2, steel, KITLG, kitl, kl-1, mgf, scf
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN650422
Quantity 100 µL
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen A synthetic peptide corresponding to residues near the N-terminus of human SCF was used as an immunogen.
Specificity A synthetic peptide corresponding to residues near the N-terminus of human SCF was used as an immunogen.
Alternative Name SCF
Background Novel hematopoietic growth factor, stem cell factor (SCF), was cloned and demonstrated to be the ligand for the c-kit tyrosine kinase receptor. SCF is encoded by Sl (steel), a gene critical to the development of several distinct cell lineages during embryonic life and which has important effects on hematopoiesis in the adult (1). SCF is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow cultures. SCF exhibits potent synergistic activities in conjunction with colony-stimulating factors, resulting in increased colony numbers and colony size (2).
Synonyms: KITLG, MGF, SCF, Kit ligand, Mast cell growth factor
Molecular Weight 18 kDA
Gene ID 4254
UniProt P21583
Research Area Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Application Notes The suggested dilution is: WB: ~~ 1:50000~200000 IP: ~~ 1,50 FC: ~~ 1,60 ICC: ~~ 1:100~250 IHC: ~~ 1:100~250
Comment

Background: Novel hematopoietic growth factor, stem cell factor (SCF), was cloned and demonstrated to be the ligand for the c-kit tyrosine kinase receptor. SCF is encoded by Sl (steel), a gene critical to the development of several distinct cell lineages during embryonic life and which has important effects on hematopoiesis in the adult (1). SCF is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow cultures. SCF exhibits potent synergistic activities in conjunction with colony-stimulating factors, resulting in increased colony numbers and colony size (2).

Restrictions For Research Use only
Format Liquid
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Preservative Sodium azide
Storage -20 °C
Storage Comment SCF Antibody can be stored at -20°C for up to 12 months from time of receipt.
Expiry Date 12 months
Background publications Geissler, Liao, Brook et al.: "Stem cell factor (SCF), a novel hematopoietic growth factor and ligand for c-kit tyrosine kinase receptor, maps on human chromosome 12 between 12q14.3 and 12qter." in: Somatic cell and molecular genetics, Vol. 17, Issue 2, pp. 207-14, 1991 (PubMed).

Martin, Suggs, Langley et al.: "Primary structure and functional expression of rat and human stem cell factor DNAs." in: Cell, Vol. 63, Issue 1, pp. 203-11, 1990 (PubMed).

Alternatives for antigen "KIT Ligand (KITLG)", type "Antibodies"
Hosts (119), (39), (17)
Reactivities (131), (61), (44), (2), (1), (1), (1), (1), (1)
Applications (130), (109), (23), (19), (17), (14), (10), (9), (9), (6), (4), (4), (3), (2), (1), (1), (1)
Conjugates (23), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
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