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Deoxynucleotidyltransferase, terminal (DNTT) antibody

Antigen

Deoxynucleotidyltransferase, terminal (DNTT)
Synonyms TDT, Tdt, BB160593, DNTT, MGC109152, dntt-A, TdT
Clonality Monoclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN650526
Quantity 100ul  (Variants)
Price 450.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name TDT
Gene ID 1791
UniProt P04053
Immunogen A synthetic peptide corresponding to residues on the C terminus of human TDT was used as an immunogen.
Description Other names: DNTT, TDT, DNA nucleotidylexotransferase, Terminal addition enzyme,Terminal deoxynucleotidyltransferase
Characteristics Rabbit Monoclonal Antibody
Specificity A synthetic peptide corresponding to residues on the C terminus of human TDT was used as an immunogen.
Molecular Weight 58 kDA
Comments

Background: Terminal deoxynucleotidyl transferase (TDT) is a unique DNA polymerase that changes the addition of deoxynucleoside 5ﾒ-triphosphate to the 3ﾒ-end of a DNA initiator without template direction (1). TDT contributes to the generation of junctional diversity in antigen receptors of immature lymphocytes, and its expression serves as a developmental marker for the sites of teleost lymphopoiesis (2). TDT is also an oligoclonal marker characterizing several populations of undifferentiated or poorly differentiated blasts that tend to develop towards or along the lymphoid pathway. Together with specific immunological markers, this enzyme is useful to define the particular type of leukemic cells (3).

Application Details
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Application Notes The suggested dilution is: WB: ~~ 1:1000~5000 IP: ~~ 1:20 ICC: ~~ 1:100~250
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage TDT Antibody can be stored at -20°C for up to 12 months from time of receipt.
Research Area Protein Modifications, Signaling, Chromatin, Cell Structure
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product "The universal protein resource (UniProt)." in: Nucleic acids research, Vol. 36, Issue Database issue, pp. D190-5, 2008 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Deoxynucleotidyltransferase, terminal (DNTT)", type "Antibodies"
Hosts Rabbit (49), Mouse (21)
Reactivities Human (54), Rat (Rattus) (28), Mouse (Murine) (27), Dog (Canine) (21), Horse (Equine) (18), Cow (Bovine) (6), Chicken (4), Cat (Feline) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (25), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunofluorescence (IF) (16), ELISA (13), Flow Cytometry (FACS) (6), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (5), Immunoprecipitation (IP) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates FITC (4), PE (3), Biotin (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (9), C-Term (6), AA 472-486 (1), Internal Region (1)