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Details for Product No. ABIN650630

Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) antibody

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Antigen
Synonyms AL024345, AW047647, 5730461F13Rik, NFLS, hSpred1, spred-1, fb14c08, fj51c03, zgc:85707, wu:fb14c08, wu:fj51c03, Xspred1, Xtspred1
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN650630
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SPRED1 antibody is generated from rabbits immunized with human SPRED1 recombinant protein.
Clone RB23008
Isotype Ig
Specificity This SPRED1 antibody is generated from rabbits immunized with human SPRED1 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SPRED1
Background SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Synonyms: Sprouty-related, EVH1 domain-containing protein 1, Spred-1, SPRED1,
Molecular Weight 50477 Da
Gene ID 161742
UniProt Q7Z699
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yoshida, Hisamoto, Akiba et al.: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).

Brems, Chmara, Sahbatou et al.: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).

Alternatives for antigen "Sprouty-Related, EVH1 Domain Containing 1 (SPRED1)", type "Antibodies"
Hosts (30), (6)
Reactivities (36), (18), (13)
Applications (36), (17), (14), (10), (2)
Epitopes (5), (4), (4), (4), (4), (3), (2), (2)
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