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SPRED1 antibody (Sprouty-Related, EVH1 Domain Containing 1)

Details for Product anti-SPRED1 Antibody No. ABIN650630, Supplier: Log in to see
Antigen
  • fb14c08
  • fj51c03
  • zgc:85707
  • wu:fb14c08
  • wu:fj51c03
  • Xspred1
  • Xtspred1
  • 5730461F13Rik
  • AL024345
  • AW047647
  • NFLS
  • hSpred1
  • spred-1
  • sprouty-related, EVH1 domain containing 1
  • SPRED1
  • sprouty protein with EVH-1 domain 1, related sequence
  • spred1
  • SPRED1
  • Bm1_51610
  • Spred1
Reactivity
Human
111
21
13
Host
Rabbit
76
35
Clonality (Clone)
Polyclonal ()
Conjugate
This SPRED1 antibody is un-conjugated
8
8
8
8
7
7
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
105
77
41
16
14
4
3
3
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Immunogen This SPRED1 antibody is generated from rabbits immunized with human SPRED1 recombinant protein.
Clone RB23008
Isotype Ig
Specificity This SPRED1 antibody is generated from rabbits immunized with human SPRED1 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SPRED1 (SPRED1 Antibody Abstract)
Background SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Synonyms: Sprouty-related, EVH1 domain-containing protein 1, Spred-1, SPRED1,
Molecular Weight 50477 Da
Gene ID 161742
UniProt Q7Z699
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SPRED1 antibody (Sprouty-Related, EVH1 Domain Containing 1) (ABIN650630) Western blot analysis of SPRED1 Antibody (ABIN650630) in Jurkat cell line lysates (35...
Flow Cytometry (FACS) image for anti-SPRED1 antibody (Sprouty-Related, EVH1 Domain Containing 1) (ABIN650630) SPRED1 Antibody (ABIN650630) flow cytometry analysis of Jurkat cells (bottom histogra...
Background publications Brems, Chmara, Sahbatou, Denayer, Taniguchi, Kato, Somers, Messiaen, De Schepper, Fryns, Cools, Marynen, Thomas, Yoshimura, Legius: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).

Yoshida, Hisamoto, Akiba, Koga, Nakamura, Tokunaga, Hanada, Kumemura, Maeyama, Harada, Ogata, Yano, Kojiro, Ueno, Yoshimura, Sata: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).