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Sorting Nexin 6 (SNX6) antibody

Details for Product No. ABIN650638, Supplier: Login to see
Antigen
  • MGC75952
  • MGC80251
  • im:7146294
  • wu:fa55b10
  • zgc:110798
  • MSTP010
  • TFAF2
  • 2010006G21Rik
  • 2610032J07Rik
  • 2810425K19Rik
  • AU018928
  • C85963
Alternatives
anti-Human Sorting Nexin 6 antibody for Enzyme Immunoassay
Reactivity
Human
67
6
5
Host
Rabbit
48
19
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
5
5
5
1
Application
Western Blotting (WB)
59
41
2
1
1
1
Supplier
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Immunogen This SNX6 antibody is generated from rabbits immunized with human SNX6 recombinant protein.
Clone RB23004
Isotype Ig
Specificity This SNX6 antibody is generated from rabbits immunized with human SNX6 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SNX6 (SNX6 Antibody Abstract)
Background SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor p
Synonyms: TRAF4-associated factor 2, Sorting nexin-6
Molecular Weight 46649 DA
Gene ID 58533
UniProt Q9UNH7
Research Area Stem Cells, Cell Cycle, Cell Structure
Pathways EGFR Signaling Pathway
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sorting Nexin 6 (SNX6) antibody (ABIN650638) Western blot analysis of SNX6 Antibody (ABIN650638) in HL-60 cell line lysates (35 µg...
Background publications Parks, Frank, Huff et al.: "Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19332-9, 2001 (PubMed).