Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2) antibody

Details for Product No. ABIN650641
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Antigen
Reactivity
Human
(71), (28), (21), (2), (1), (1), (1), (1)
Host
Rabbit
(45), (25), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(64), (31), (23), (10), (7), (6), (4), (2), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN650641
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Immunogen This ALDH3A2 antibody is generated from rabbits immunized with human ALDH3A2 recombinant protein.
Clone RB23016
Isotype Ig
Specificity This ALDH3A2 antibody is generated from rabbits immunized with human ALDH3A2 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ALDH3A2
Background Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome.
Synonyms: Fatty aldehyde dehydrogenase, Aldehyde dehydrogenase, microsomal, Aldehyde dehydrogenase family 3 member A2, Aldehyde dehydrogenase 10, ALDH3A2, ALDH10, FALDH,
Molecular Weight 54848 DA
Gene ID 224
UniProt P51648
Research Area Stem Cells
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2) antibody Western blot analysis of ALDH3A2 Antibody (ABIN650641) in Hela, HepG2, WiDr cell line lysates (35 µg/lane). ALDH3A2 (arrow) was detected using the purified polyclonal antibody.
anti-Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2) antibody (2) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ALDH3A2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2) antibody (3) Western blot analysis of ALDH3A2 (arrow) using rabbit polyclonal ALDH3A2 Antibody (ABIN650641). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ALDH3A2 gene.
Background publications Pigg, Jagell, Sillén et al.: "The Sjögren-Larsson syndrome gene is close to D17S805 as determined by linkage analysis and allelic association." in: Nature genetics, Vol. 8, Issue 4, pp. 361-4, 1995 (PubMed).

De Laurenzi, Rogers, Hamrock et al.: "Sjögren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene." in: Nature genetics, Vol. 12, Issue 1, pp. 52-7, 1996 (PubMed).

Rogers, Markova, De Laurenzi et al.: "Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH)." in: Genomics, Vol. 39, Issue 2, pp. 127-35, 1997 (PubMed).

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