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VEGFC antibody

VEGFC Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB22679 unconjugated
Catalog No. ABIN650694
  • Target See all VEGFC Antibodies
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    Reactivity
    • 97
    • 57
    • 39
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 94
    • 29
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 99
    • 27
    Polyclonal
    Conjugate
    • 50
    • 17
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This VEGFC antibody is un-conjugated
    Application
    • 116
    • 56
    • 47
    • 26
    • 26
    • 25
    • 14
    • 10
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This VEGFC antibody is generated from rabbits immunized with VEGFC recombinant protein.
    Clone
    RB22679
    Isotype
    IgG
    Top Product
    Discover our top product VEGFC Primary Antibody
  • Application Notes
    WB: 1:2000. WB: 1:2000. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Dai, Liu, Liu, Zhang, Wang, Jin, Qian, Wang, Zhao, Wu, Xiong, Chang, Sun, Yang, Hoffman, Liu: "Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model." in: Anticancer research, Vol. 37, Issue 3, pp. 979-986, (2017) (PubMed).

    Zhao, Hou, Hou, Zhu: "Concurrent Expression of VEGF-C and Neuropilin-2 Is Correlated with Poor Prognosis in Glioblastoma." in: The Tohoku journal of experimental medicine, Vol. 238, Issue 2, pp. 85-91, (2016) (PubMed).

    Yang, Wang, Dong, Shen, Guo, Liu, Liu, Zhang, Li, Sun: "Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways." in: American journal of cancer research, Vol. 5, Issue 10, pp. 3085-97, (2015) (PubMed).

    Shi, Yang, Shen, Yang, Xu, Qiu, Sun, Zhang, Wang, Zhu, Qin, Tang, Fan, Zhou: "High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery." in: Cancer, Vol. 119, Issue 5, pp. 993-1003, (2013) (PubMed).

    Hirata, Hinoda, Ueno, Shahryari, Tabatabai, Dahiya: "MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer." in: Carcinogenesis, Vol. 33, Issue 1, pp. 41-8, (2011) (PubMed).

  • Target
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    Alternative Name
    VEGFC (VEGFC Products)
    Synonyms
    VEGFC antibody, vegf-c antibody, xvegf-c antibody, Flt4-L antibody, VRP antibody, AW228853 antibody, VEGF-C antibody, vascular endothelial growth factor c antibody, vascular endothelial growth factor C antibody, vascular endothelial growth factor C S homeolog antibody, vegfc antibody, VEGFC antibody, vegfc.S antibody, Vegfc antibody
    Background
    VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
    Molecular Weight
    46883
    Gene ID
    7424
    NCBI Accession
    NP_005420
    UniProt
    P49767
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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