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Details for Product No. ABIN650755

Defective in Sister Chromatid Cohesion 1 Homolog (S. Cerevisiae) (DSCC1) (C-Term), (AA 311-339) antibody

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Antigen
Synonyms 2010006I05Rik, 2600005O03Rik, Dcc1, DCC1, RGD1561749, zgc:103507
Epitope
»Alternatives C-Term, AA 311-339
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN650755
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 AA from the C-terminal region of human DCC1.
Clone RB27627
Isotype Ig
Specificity This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the C-terminal region of human DCC1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DCC1
Background CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176], Bermudez et al., 2003 [PubMed 12930902]).
Synonyms: Sister chromatid cohesion protein DCC1,DSCC1,DCC1
Molecular Weight 44825 DA
Gene ID 79075
UniProt Q9BVC3, NP_076999.2
Research Area Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Merkle, Karnitz, Henry-Sánchez et al.: "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30051-6, 2003 (PubMed).

Terret, Sherwood, Rahman et al.: "Cohesin acetylation speeds the replication fork." in: Nature, Vol. 462, Issue 7270, pp. 231-4, 2009 (PubMed).

Murakami, Takano, Takeo et al.: "Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34608-15, 2010 (PubMed).

Alternatives for antigen "Defective in Sister Chromatid Cohesion 1 Homolog (S. Cerevisiae) (DSCC1)", type "Antibodies"
Hosts (18), (2)
Reactivities (20), (11), (11), (11), (11)
Applications (11), (9), (3), (3), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1), (1), (1)
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