Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody

Details for Product No. ABIN650759, Supplier: Log in to see
Antigen
  • cfl1
  • xac1
  • xac2
  • cfl
  • cb86
  • sb:cb86
  • zgc:56501
  • wu:fb18a04
  • wu:fk77b03
  • 12/8
  • ADF
  • ADF/cofilin
  • Adf
  • CG4254
  • Cadf
  • D-cof
  • D61
  • Dmel\\CG4254
  • T8
  • Tsr
  • cofilin
  • cofilin/ADF
  • cofilin/actin depolymerizing factor homolog
  • l(2)03101
  • l(2)k03101
  • l(2)k05633
  • l(2)k13409
  • ntf
  • CFL
  • AA959946
  • Cof
  • CFL1
  • cofilin 1 (non-muscle)
  • twinstar
  • Cof1p
  • cofilin
  • cofilin 1 (non-muscle)-like
  • cofilin 1, non-muscle
  • COFILIN protein
  • Contrafreeloading
  • cfl1-a
  • cfl1
  • CFL1
  • tsr
  • COF1
  • TSTA_042790
  • Cfl1
  • LOC100341589
  • COFILIN
  • CFL
Alternatives
anti-Mouse (Murine) Cofilin 1 (Non-Muscle) antibody for Confocal Microscopy
Epitope
AA 70-98, Center
58
38
28
23
15
14
14
13
10
10
6
5
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
324
197
161
12
11
9
7
5
2
2
1
1
1
1
Host
Rabbit
258
62
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
13
13
11
9
8
7
4
4
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
229
131
105
69
65
41
39
29
17
7
5
4
4
3
2
1
Options
Supplier
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Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 AA from the Central region of human CFL1.
Clone RB23947
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77~106 amino acids from the Center region of human CFL1.
Predicted Reactivity Cow (Bovine),Chicken,Pig (Porcine),Monkey,Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CFL1 (CFL1 Antibody Abstract)
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Pathways Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in HL-60 cell line lysat...
Western Blotting (WB) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in mouse NIH-3T3 cell li...
Flow Cytometry (FACS) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) CFL1 Antibody (Center) (ABIN650759) flow cytometric analysis of HL-60 cells (bottom h...
Background publications Fazal, Bijli, Minhajuddin, Rein, Finkelstein, Rahman: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).