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Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody

Details for Product No. ABIN650759, Supplier: Log in to see
Antigen
  • 12/8
  • AA959946
  • ADF
  • Adf
  • ADF/cofilin
  • Cadf
  • cb86
  • CFL
  • cfl
  • CFL1
  • cfl1
  • CG4254
  • Cof
  • cofilin
  • cofilin/actin depolymerizing factor homolog
  • cofilin/ADF
  • D-cof
  • D61
  • Dmel\\CG4254
  • l(2)03101
  • l(2)k03101
  • l(2)k05633
  • l(2)k13409
  • ntf
  • sb:cb86
  • T8
  • Tsr
  • wu:fb18a04
  • wu:fk77b03
  • xac1
  • xac2
  • zgc:56501
Epitope
AA 70-98, Center
55
31
28
20
19
15
14
13
13
10
9
6
5
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
304
141
128
8
8
4
4
2
2
1
1
1
1
Host
Rabbit
241
60
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
12
11
11
8
7
7
4
4
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
216
134
98
54
49
35
19
18
11
4
4
2
2
1
Supplier
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Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 AA from the Central region of human CFL1.
Clone RB23947
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77~106 amino acids from the Center region of human CFL1.
Predicted Reactivity Cow (Bovine),Chicken,Pig (Porcine),Monkey,Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CFL1 (CFL1 Antibody Abstract)
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in HL-60 cell line lysat...
Western Blotting (WB) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in mouse NIH-3T3 cell li...
Flow Cytometry (FACS) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (ABIN650759) CFL1 Antibody (Center) (ABIN650759) flow cytometric analysis of HL-60 cells (bottom h...
Background publications Fazal, Bijli, Minhajuddin, Rein, Finkelstein, Rahman: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009