Add to Basket
|+1 404 474 4654|
|+1 888 205 9894 (TF)|
APG8c (MAP1LC3C) (pTyr105) antibody
Dot Blot (Dot), ELISA
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This Phospho-APG8c (MAP1LC3C)-Y105 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 91~121 amino acids surrounding Y105 of human APG8c (MAP1LC3C).|
|Description||Other names: Autophagy-related ubiquitin-like modifier LC3 C, Autophagy-related protein LC3 C, MAP1 light chain 3-like protein 3, MAP1A/MAP1B light chain 3 C, MAP1A/MAP1B LC3 C, Microtubule-associated protein 1 light chain 3 gamma, Microtubule-associated proteins 1A/1B light chain 3C, MAP1LC3C|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This Phospho-APG8c (MAP1LC3C)-Y105 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 91~121 amino acids surrounding Y105 of human APG8c (MAP1LC3C).|
|Molecular Weight||16852 DA|
Background: APG8c is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. APG8c is 1 of 3 orthologs of the yeast autophagosome protein Atg8.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Dot Blot~~ 1:500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Protein Modifications, Phospho-specific antibodies|
|Restrictions||For Research Use only|
|Dot blot analysis of anti-Phospho-APG8c (MAP1LC3C)-Y105 Phospho-specific Pab (ABIN650831) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.|
He, Dang, Dai et al.: "Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 29278-87, 2003 (PubMed).
Tanida, Sou, Ezaki et al.: "HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates." in: The Journal of biological chemistry, Vol. 279, Issue 35, pp. 36268-76, 2004 (PubMed).