APG8b (MAP1LC3B) (AA 89-122), (cleaved) antibody

Details for Product No. ABIN650885
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AA 89-122, cleaved
(1), (1), (1), (1), (1), (1), (1), (1)
(4), (1)
Clonality (Clone)
Polyclonal ()
Dot Blot (DB)
(2), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN650885
Quantity 400 µL
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Immunogen This Cleaved antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-122 AA from human Cleaved.
Clone RB28608
Isotype Ig
Specificity This Cleaved-APG8b (MAP1LC3B) Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human APG8b.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Synonyms: Microtubule-associated proteins 1A/1B light chain 3B,MAP1LC3B,MAP1ALC3
Molecular Weight 14688 DA
Gene ID 81631
UniProt NP_073729, Q9GZQ8
Research Area Cell Structure, Autophagy
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-APG8b (MAP1LC3B) (AA 89-122), (cleaved) antibody Dot blot analysis of anti-Cleaved-APG8b (MAP1LC3B) Phospho-specific Pab (ABIN650885) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL.
Background publications Kirkin, Lamark, Sou et al.: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).

Hosts (4)
Reactivities (4), (1)
Applications (2), (2), (2), (2)
Epitopes (1), (1), (1), (1), (1), (1), (1), (1)
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