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SOX2 antibody (pSer246)

SOX2 Reactivity: Human IF, DB Host: Rabbit Polyclonal RB26203 unconjugated
Catalog No. ABIN650887
  • Target See all SOX2 Antibodies
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Binding Specificity
    • 18
    • 16
    • 16
    • 16
    • 16
    • 15
    • 13
    • 12
    • 10
    • 9
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer246
    Reactivity
    • 203
    • 96
    • 69
    • 21
    • 13
    • 11
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 165
    • 42
    • 2
    Rabbit
    Clonality
    • 162
    • 47
    Polyclonal
    Conjugate
    • 103
    • 16
    • 15
    • 10
    • 10
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOX2 antibody is un-conjugated
    Application
    • 166
    • 109
    • 47
    • 46
    • 44
    • 40
    • 40
    • 27
    • 26
    • 26
    • 18
    • 15
    • 12
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Dot Blot (DB)
    Predicted Reactivity
    M, Sh
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Sox2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S246 of human Sox2.
    Clone
    RB26203
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SOX2 Primary Antibody
  • Application Notes
    IF: 1:200. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Alternative Name
    Sox2 (SOX2 Products)
    Synonyms
    ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
    Background
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
    Molecular Weight
    34310
    Gene ID
    6657
    NCBI Accession
    NP_003097
    UniProt
    P48431
    Pathways
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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