BHLHE22 antibody (AA 236-264)

Catalog No. ABIN650975

Product Details anti-BHLHE22 Antibody

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Binding Specificity: AA 236-264

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHE22 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BHLHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the Central region of human BHLHB5.

Clone: RB25879

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Alternative Name: BHLHB5 (BHLHE22 Products)

Synonyms: bhlhb5 antibody, MGC145865 antibody, BHLHE22 antibody, Beta3.1 antibody, wu:fq25e11 antibody, zgc:64225 antibody, BHLHB5 antibody, Beta3 antibody, CAGL85 antibody, TNRC20 antibody, Bhlhb5 antibody, basic helix-loop-helix family member e22 antibody, basic helix-loop-helix family, member e22 antibody, bhlhe22 antibody, BHLHE22 antibody, Bhlhe22 antibody

Background: BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.

Gene ID: 27319

NCBI Accession: NP_689627

UniProt: Q8NFJ8