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FA2H antibody (Fatty Acid 2-Hydroxylase) (AA 121-148)

Details for Product anti-FA2H Antibody No. ABIN650994, Supplier: Log in to see
Antigen
  • MGC85470
  • MGC97767
  • cb1044
  • zgc:153777
  • FAAH
  • FAH1
  • FAXDC1
  • SCS7
  • SPG35
  • Faxdc1
  • G630055L08Rik
  • RGD1310347
  • Wdr59
  • fatty acid 2-hydroxylase
  • fatty acid hydroxylase
  • fa2h
  • FA2H
  • Tsp_11648
  • Ilyop_0703
  • Ftrac_1469
  • Ftrac_3310
  • Celal_3558
  • Celal_4047
  • Pedsa_2221
  • Pedsa_3694
  • Celly_1453
  • Weevi_1515
  • Fluta_1455
  • Halhy_6587
  • Halhy_1608
  • Mesop_3301
  • Fa2h
Epitope
AA 121-148, Center
14
7
7
4
3
1
1
1
Reactivity
Human, Mouse (Murine)
41
20
7
1
1
1
1
Host
Rabbit
33
10
Clonality (Clone)
Polyclonal ()
Conjugate
This FA2H antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
20
19
6
2
1
Options
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Immunogen This FA2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 AA from the Central region of human FA2H.
Clone RB23881
Isotype Ig
Specificity This FA2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127~157 amino acids from the Central region of human FA2H.
Predicted Reactivity Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FA2H (FA2H Antibody Abstract)
Background FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
Synonyms: Fatty acid alpha-hydroxylase, Fatty acid 2-hydroxylase,FAAH, FA2H
Molecular Weight 42791 DA
Gene ID 79152
UniProt Q7L5A8
Research Area Cell Signaling, Cell Structure, Metabolism, Neurology
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-FA2H antibody (Fatty Acid 2-Hydroxylase) (AA 121-148) (ABIN650994) Western blot analysis of FA2H Antibody (Center) (ABIN650994) in ZR-75-1 cell line lys...
Western Blotting (WB) image for anti-FA2H antibody (Fatty Acid 2-Hydroxylase) (AA 121-148) (ABIN650994) Western blot analysis of FA2H Antibody (Center) (ABIN650994) in mouse brain tissue ly...
Immunohistochemistry (IHC) image for anti-FA2H antibody (Fatty Acid 2-Hydroxylase) (AA 121-148) (ABIN650994) FA2H Antibody (Center) (ABIN650994) IHC analysis in formalin fixed and paraffin embed...
Background publications Uchida, Hama, Alderson, Douangpanya, Wang, Crumrine, Elias, Holleran: "Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 18, pp. 13211-9, 2007 (PubMed).