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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC) (C-Term) antibody
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml) (Variants)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This EEFSEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553~582 amino acids from the C-terminal region of human EEFSEC.|
|Description||Other names: Eukaryotic elongation factor, selenocysteine-tRNA-specific, Elongation factor sec, Selenocysteine-specific elongation factor,SELB, EEFSEC|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This EEFSEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553~582 amino acids from the C-terminal region of human EEFSEC.|
|Molecular Weight||65305 DA|
Background: EEFSEC is translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100 Flow cytometric~~1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Translation Factors, Chromatin, Signaling, Cell Structure|
|Restrictions||For Research Use only|
Muzny, Scherer, Kaul et al.: "The DNA sequence, annotation and analysis of human chromosome 3." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).
Donovan, Caban, Ranaweera et al.: "A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 35129-39, 2008 (PubMed).
Gudmundsson, Sulem, Gudbjartsson et al.: "Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility." in: Nature genetics, Vol. 41, Issue 10, pp. 1122-6, 2009 (PubMed).
|Reactivities||Human (12), Mouse (Murine) (5), Rat (Rattus) (4), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (10), ELISA (9), Immunohistochemistry (IHC) (4), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)|
|Epitopes||C-Term (4), C-Term,AA 547-577 (1), C-Term,AA 553-582 (1)|