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Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET) (Tyr1234, Tyr1235) antibody

Antigen

Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET)
Synonyms SF, HGFB, HPTA, F-TCF, DFNB39, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, HGF, CACNA2D1, MET
Binding Site
Alternatives

Tyr1234, Tyr1235
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN651050
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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anti-Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET) (Tyr1234, Tyr1235) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name Met
Gene ID 4233
UniProt P08581
Immunogen This MET (Y1234/1235) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1219~1248 amino acids from the Y1234/1235 region of human MET.
Isotype Ig
Description Other names: Proto-oncogene c-Met, Tyrosine-protein kinase Met, HGF/SF receptor, Scatter factor receptor, SF receptor, Hepatocyte growth factor receptor, HGF receptor,MET
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This MET (Y1234/1235) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1219~1248 amino acids from the Y1234/1235 region of human MET.
Molecular Weight 155541 DA
Comments

Background: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling
Restrictions For Research Use only

Publications
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Product Turke, Zejnullahu, Wu et al.: "Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC." in: Cancer cell, Vol. 17, Issue 1, pp. 77-88, 2010 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET)", type "Antibodies"
Hosts Rabbit (121), Mouse (17), Rat (Rattus) (1)
Reactivities Human (135), Mouse (Murine) (81), Rat (Rattus) (70), Cow (Bovine) (16), Dog (Canine) (16), Pig (Porcine) (15), Sheep (Ovine) (15), Guinea Pig (10), Horse (Equine) (10), Chicken (6), Cat (Feline) (1)
Applications Western Blotting (WB) (84), ELISA (38), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (33), Immunofluorescence (IF) (28), Immunohistochemistry (IHC) (16), Immunocytochemistry (ICC) (4), Immunoprecipitation (IP) (4), Dot Blot (Dot) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Cell-ELISA (cELISA) (1), Flow Cytometry (FACS) (1), Fluorescence Microscopy (FM) (1)
Conjugates Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), PE,Cy5.5 (4)
Epitopes pTyr1349 (13), pTyr1234 (7), pTyr1003 (6), pTyr1235,pTyr1234 (5), pTyr1365 (4), C-Term (3), Tyr1234 (2), Tyr1349 (2), pTyr1234,pTyr1235 (2), pTyr1356 (2), N-Term (1), Phosphospecific (1), Tyr1003 (1), pSer222,pSer218 (1), pSer62,pThr58 (1), pTyr1249,pTyr1356 (1), pTyr1356,pTyr1349 (1)