Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (C-Term), (AA 713-742) antibody

Details for Product No. ABIN651060
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Antigen
Synonyms GR, GCR, GRL, GCCR, Grl1, Grl-1, Gcr, Grl, GR-A, NO, gcr, grl, xGR, gccr, gr, zgc:113038, NR3C1, GCL, nr3c1, LOC100302444
Epitope
C-Term, AA 713-742
(20), (13), (8), (7), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(139), (62), (61), (13), (3), (2), (1), (1)
Host
Rabbit
(113), (35), (7)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(9), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(116), (62), (42), (31), (31), (30), (28), (17), (15), (15), (3), (3), (3), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN651060
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-742 AA from the C-terminal region of human NR3C1.
Clone RB26107
Isotype Ig
Specificity This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 712-742 from the C-terminal region of human NR3C1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NR3C1
Background NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
Synonyms: Nuclear receptor subfamily 3 group C member 1, Glucocorticoid receptor, GR,GRL, NR3C1
Molecular Weight 81509 DA
Gene ID 2908
UniProt P04150-2
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (C-Term), (AA 713-742) antibody Western blot analysis of NR3C1 Antibody (C-term) (ABIN651060) in A549 cell line lysates (35 µg/lane). NR3C1 (arrow) was detected using the purified polyclonal antibody.
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (C-Term), (AA 713-742) antibody (2) NR3C1 Antibody (C-term) (ABIN651060) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Wang, Frederick, Garabedian: "Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26573-80, 2002 (PubMed).

Geelhoed, Steegers, Koper et al.: "Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study." in: BMC medical genetics, Vol. 11, pp. 39, 2010 (PubMed).

Hosts (113), (35), (7)
Reactivities (139), (62), (61), (13), (3), (2), (1), (1)
Applications (116), (62), (42), (31), (31), (30), (28), (17), (15), (15), (3), (3), (3), (1), (1), (1), (1)
Conjugates (9), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Epitopes (20), (13), (8), (7), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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