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BBS10 antibody (C-Term)

BBS10 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24715 unconjugated
Catalog No. ABIN651074
  • Target See all BBS10 Antibodies
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 515-544, C-Term
    Reactivity
    • 39
    • 2
    • 1
    • 1
    Human
    Host
    • 38
    • 1
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BBS10 antibody is un-conjugated
    Application
    • 35
    • 20
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BBS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-544 amino acids from the C-terminal region of human BBS10.
    Clone
    RB24715
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BBS10 Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Alternative Name
    BBS10 (BBS10 Products)
    Synonyms
    MGC84945 antibody, si:dkey-30c15.16 antibody, C12orf58 antibody, RGD1560748 antibody, 1300007O09Rik antibody, AI452285 antibody, Bardet-Biedl syndrome 10 antibody, Bardet-Biedl syndrome 10 L homeolog antibody, Bardet-Biedl syndrome 10 (human) antibody, BBS10 antibody, bbs10.L antibody, bbs10 antibody, Bbs10 antibody
    Background
    BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.
    Molecular Weight
    80838
    Gene ID
    79738
    NCBI Accession
    NP_078961
    UniProt
    Q8TAM1
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