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CHRNA3 antibody (N-Term)

CHRNA3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB25608 unconjugated
Catalog No. ABIN651212
  • Target See all CHRNA3 Antibodies
    CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 25-52, N-Term
    Reactivity
    • 57
    • 19
    • 18
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 2
    Rabbit
    Clonality
    • 55
    • 2
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNA3 antibody is un-conjugated
    Application
    • 48
    • 22
    • 21
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CHRNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3.
    Clone
    RB25608
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CHRNA3 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Pfaender, Föhr, Lutz, Putz, Achberger, Linta, Liebau, Boeckers, Grabrucker: "Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells." in: Neural plasticity, Vol. 2016, pp. 3760702, (2016) (PubMed).

  • Target
    CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
    Alternative Name
    CHRNA3 (CHRNA3 Products)
    Synonyms
    LNCR2 antibody, NACHRA3 antibody, PAOD2 antibody, (a)3 antibody, A730007P14Rik antibody, Acra-3 antibody, Acra3 antibody, cholinergic receptor nicotinic alpha 3 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 3 antibody, CHRNA3 antibody, Chrna3 antibody
    Background
    CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
    Molecular Weight
    57480
    Gene ID
    1136
    NCBI Accession
    NP_000734, NP_001160166
    UniProt
    P32297
    Pathways
    Synaptic Membrane
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