Mal, T-Cell Differentiation Protein-Like (MALL) (Center) antibody

Antigen: Mal, T-Cell Differentiation Protein-Like (MALL)

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651248

Additional Information

Alternative name: MALL

Gene ID: 7851

UniProt: Q13021

Immunogen: This MALL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of human MALL.

Isotype: Ig

Description: Other names: Protein BENE, MAL-like protein,BENE, MALL

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This MALL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of human MALL.

Molecular Weight: 17350 DA

Comments:

Background: MALL encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of MALL Antibody (Center) (ABIN651248) in NCI-H460 cell line lysates (35ug/lane).MALL (arrow) was detected using the purified Pab.

MALL Antibody (Center) (ABIN651248) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Publications

Product: Hildebrandt, Otto, Rensing et al.: "A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1." in: Nature genetics, Vol. 17, Issue 2, pp. 149-53, 1997 (PubMed).

Saunier, Calado, Heilig et al.: "A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis." in: Human molecular genetics, Vol. 6, Issue 13, pp. 2317-23, 1998 (PubMed).