|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Helicase, Lymphoid-Specific (HELLS) (N-Term) antibody
|Synonyms||LSH, PASG, SMARCA6, FLJ10339, Nbla10143, HELLS, cb65, pasg, sb:cb65, sb:cb749, im:6911667|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This HELLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human HELLS.|
|Description||Other names: Lymphoid-specific helicase,HELLS,SMARCA6, PASG|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This HELLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human HELLS.|
|Molecular Weight||97074 DA|
Background: HELLS is a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Chromatin, Metabolism, Cell Structure|
|Restrictions||For Research Use only|
Suzuki, Farrar, Yegnasubramanian et al.: "Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts." in: Epigenetics : official journal of the DNA Methylation Society, Vol. 3, Issue 5, pp. 281-91, 2008 (PubMed).
Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).
Zhou, Han, Li et al.: "Senescence delay and repression of p16INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts." in: Nucleic acids research, Vol. 37, Issue 15, pp. 5183-96, 2009 (PubMed).
|Hosts||Rabbit (30), Mouse (1)|
|Reactivities||Human (30), Mouse (Murine) (23), Rat (Rattus) (21), Cow (Bovine) (20), Horse (Equine) (18), Pig (Porcine) (18), Dog (Canine) (2), Cat (Feline) (1), Chicken (1), Xenopus laevis (1)|
|Applications||Immunofluorescence (IF) (16), Western Blotting (WB) (16), ELISA (12), Immunohistochemistry (IHC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (3), Immunoelectron Microscopy (IEM) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||Center (3), Internal Region (1)|