Olfactory Receptor, Family 10, Subfamily H, Member 3 (OR10H3) (C-Term) antibody

Antigen: Olfactory Receptor, Family 10, Subfamily H, Member 3 (OR10H3)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651355

Additional Information

Alternative name: OR10H3

Gene ID: 26532

UniProt: O60404

Immunogen: This OR10H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-280 amino acids from the C-terminal region of human OR10H3.

Isotype: Ig

Description: Other names: Olfactory receptor OR19-24, Olfactory receptor 10H3,OR10H3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OR10H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-280 amino acids from the C-terminal region of human OR10H3.

Molecular Weight: 35721 DA

Comments:

Background: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling

Restrictions: For Research Use only

Images

Western blot analysis of OR10H3 Antibody (C-term) (ABIN651355) in NCI-H292 cell line lysates (35ug/lane).OR10H3 (arrow) was detected using the purified Pab.

OR10H3 Antibody (C-term) (ABIN651355) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the OR10H3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).

Grimwood, Gordon, Olsen et al.: "The DNA sequence and biology of human chromosome 19." in: Nature, Vol. 428, Issue 6982, pp. 529-35, 2004 (PubMed).