DCLRE1B antibody (AA 208-236)

Catalog No. ABIN651618

Product Details anti-DCLRE1B Antibody

Target: DCLRE1B (DNA Cross-Link Repair 1B (DCLRE1B))

Binding Specificity: AA 208-236

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLRE1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DCLRE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human DCLRE1B.

Clone: RB26835

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DCLRE1B antibody (ABIN651618)

Sengerová, Allerston, Abu, Lee, Hartley, Kiakos, Schofield, Hartley, Gileadi, McHugh: "Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases." in: The Journal of biological chemistry, Vol. 287, Issue 31, pp. 26254-67, (2012) (PubMed).

Target Details for DCLRE1B

Target: DCLRE1B (DNA Cross-Link Repair 1B (DCLRE1B))

Alternative Name: DCLRE1B (DCLRE1B Products)

Synonyms: APOLLO antibody, SNM1B antibody, SNMIB antibody, im:6894074 antibody, zgc:154089 antibody, AI452214 antibody, Apollo antibody, mSNM1B antibody, DNA cross-link repair 1B antibody, DCLRE1B antibody, Dclre1b antibody, dclre1b antibody

Background: DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).

Molecular Weight: 60002

Gene ID: 64858

NCBI Accession: NP_073747

UniProt: Q9H816