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EGFR antibody (Epidermal Growth Factor Receptor) (AA 1004-1033)

Details for Product anti-EGFR Antibody No. ABIN651628, Supplier: Log in to see
Antigen
  • 9030024J15Rik
  • AI552599
  • C-erb
  • c-erbB
  • CG10079
  • D-Egf
  • d-egf-r
  • D-EGFR
  • Degfr
  • dEgfr
  • DEgfr
  • DEGFR
  • dEGFR
  • dEGFR1
  • der
  • DER
  • Der
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DER flb
  • Dmel\\CG10079
  • DmHD-33
  • EFG-R
  • Egf
  • EGF-R
  • Egf-r
  • EgfR
  • EGfr
  • EGFr
  • EGFR
  • egfr
  • egfr1
  • EGFR12
  • EGFR15
  • EK2-6
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • ERBB
  • Erbb
  • ErbB-1
  • ERBB1
  • Erbb2
  • Errb1
  • Errp
  • flb
  • HD-33
  • HER1
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57Ea
  • l(2)57EFa
  • mENA
  • mor1
  • PIG61
  • TOP
  • top
  • top/DER
  • top/flb
  • Torpedo/DER
  • Torpedo/Egfr
  • torpedo/Egfr
  • torpedo/egfr
  • wa-2
  • wa2
  • Wa5
Alternatives
anti-Human EGFR antibody for Western Blotting
Epitope
AA 1004-1033, C-Term
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138
59
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36
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2
1
1
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1
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Reactivity
Human
2196
764
625
23
16
14
13
10
8
5
4
2
1
1
1
1
1
Host
Rabbit
1397
698
69
45
7
2
Clonality (Clone)
Polyclonal ()
Conjugate
This EGFR antibody is un-conjugated
94
74
64
57
46
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44
25
23
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16
2
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1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1332
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526
447
427
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185
87
74
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25
11
11
8
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4
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3
2
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2
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2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Immunogen This EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1004-1033 AA from the C-terminal region of human EGFR-S1026.
Clone RB26905
Isotype Ig
Specificity This EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EGFR (EGFR Antibody Abstract)
Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Synonyms: EGFR,ERBB1
Molecular Weight 134277 DA
Gene ID 1956
NCBI Accession NP_005219, NP_958439, NP_958440, NP_958441
UniProt P00533
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1004-1033) (ABIN651628) EGFR-S1026 (ABIN651628) western blot analysis in K562 cell line lysates (35 µg/lane)....
Immunohistochemistry (IHC) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1004-1033) (ABIN651628) EGFR-S1026 Antibody (C-term) (ABIN651628) immunohistochemistry analysis in formalin f...
Flow Cytometry (FACS) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1004-1033) (ABIN651628) EGFR-S1026 Antibody (C-term) (ABIN651628) flow cytometric analysis of K562 cells (rig...
Background publications Lowenstein, Daly, Batzer, Li, Margolis, Lammers, Ullrich, Skolnik, Bar-Sagi, Schlessinger: "The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling." in: Cell, Vol. 70, Issue 3, pp. 431-42, 1992 (PubMed).