DAAM1 antibody (Dishevelled Associated Activator of Morphogenesis 1) (AA 341-370)

Details for Product anti-DAAM1 Antibody No. ABIN651631, Supplier: Log in to see
Antigen
  • daam-1
  • xdaam1
  • DAAM1
  • DKFZp468D0524
  • 1700066F09Rik
  • 2310028E21Rik
  • AI503486
  • E130308H01
  • mKIAA0666
  • daam1
  • dishevelled associated activator of morphogenesis 1
  • dishevelled associated activator of morphogenesis 1a
  • daam1
  • DAAM1
  • Daam1
  • daam1a
Alternatives
anti-Human DAAM1 antibody for Enzyme Immunoassay
Epitope
AA 341-370, N-Term
28
12
7
4
3
3
3
3
2
2
1
1
1
1
Reactivity
Hamster, Human
77
16
16
8
5
5
4
2
2
2
1
1
1
Host
Rabbit
71
6
Clonality (Clone)
Polyclonal ()
Conjugate
This DAAM1 antibody is un-conjugated
5
5
5
5
5
5
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
72
49
46
10
8
6
4
2
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 AA from the N-terminal region of human DAAM1-T361.
Clone RB15348
Isotype Ig
Specificity This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-378 amino acids from the N-terminal region of human DAAM1-T361.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DAAM1 (DAAM1 Antibody Abstract)
Background Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Synonyms: DAAM1,KIAA0666,Disheveled-associated activator of morphogenesis 1
Molecular Weight 123473 DA
Gene ID 23002
NCBI Accession NP_055807
UniProt Q9Y4D1
Research Area Cell Structure
Pathways WNT Signaling
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.26 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 341-370), (N-Term) antibody (ABIN651631) DAAM1-T361 Antibody (N-term) (ABIN651631) western blot analysis in WiDr cell line lys...
Western Blotting (WB) image for anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 341-370), (N-Term) antibody (ABIN651631) DAAM1-T361 Antibody (N-term) (ABIN651631) western blot analysis in CHO cell line lysa...
Immunohistochemistry (IHC) image for anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (AA 341-370), (N-Term) antibody (ABIN651631) DAAM1-T361 Antibody (N-term) (ABIN651631) immunohistochemistry analysis in formalin f...
Background publications Higashi, Ikeda, Shirakawa, Kondo, Kawato, Horiguchi, Okuda, Okawa, Fukai, Nureki, Kita, Horiuchi: "Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets." in: The Journal of biological chemistry, Vol. 283, Issue 13, pp. 8746-55, 2008 (PubMed).

Liu, Sato, Khadka, Bharti, Diaz, Runnels, Habas: "Mechanism of activation of the Formin protein Daam1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 210-5, 2008 (PubMed).

Did you look for something else?