KIAA1279 (KIAA1279) (N-Term) antibody

Antigen: KIAA1279 (KIAA1279)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651684

Additional Information

Alternative name: KBP

Gene ID: 26128

UniProt: Q96EK5, NP_056449.1

Immunogen: This KBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human KBP.

Isotype: Ig

Description: Other names: KIAA1279,KBP,KIF1-binding protein

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This KBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human KBP.

Molecular Weight: 71814 DA

Comments:

Background: KBP is a kinesin family member 1 binding protein that is characterized by two tetratrico peptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating transport of the mitochondria.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Cycle, Neurology, Cell Structure

Restrictions: For Research Use only

Images

KBP Antibody (N-term) (ABIN651684) western blot analysis in 293 cell line lysates (35ug/lane). This demonstrates the KBP antibody detected the KBP protein (arrow).

KBP Antibody (N-term) (ABIN651684) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KBP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

KBP Antibody (N-term) (ABIN651684) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Publications

Product: Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).