Zinc Finger, X-Linked, Duplicated A (ZXDA) (Center) antibody

Antigen: Zinc Finger, X-Linked, Duplicated A (ZXDA)

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651697

Additional Information

Alternative name: ZXDA

Gene ID: 7789

UniProt: NP_009087.1, P98168

Immunogen: This ZXDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-487 amino acids from the Central region of human ZXDA.

Isotype: Ig

Description: Other names: ZXDA,Zinc finger X-linked protein ZXDA

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ZXDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-487 amino acids from the Central region of human ZXDA.

Molecular Weight: 84771 DA

Comments:

Background: ZXDA is one of two duplicated zinc finger genes on chromosome Xp11. This gene is the telomeric copy, GeneID 158586 ZXDB is the more centromeric copy. The two genes have 98% nucleotide sequence similarity, and the predicted proteins contain 10 tandem zinc finger motifs.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure

Restrictions: For Research Use only

Images

ZXDA Antibody (Center) (ABIN651697) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the ZXDA antibody detected the ZXDA protein (arrow).

ZXDA Antibody (Center) (ABIN651697) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZXDA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Jambunathan, Fontes: "Sumoylation of the zinc finger protein ZXDC enhances the function of its transcriptional activation domain." in: Biological chemistry, Vol. 388, Issue 9, pp. 965-72, 2007 (PubMed).

Tarpey, Smith, Pleasance et al.: "A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation." in: Nature genetics, Vol. 41, Issue 5, pp. 535-43, 2009 (PubMed).