DDC antibody (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase)) (AA 32-61)

Details for Product anti-DDC Antibody No. ABIN651727, Supplier: Log in to see
Antigen
  • 5-HT
  • AADC
  • CG10697
  • DDC
  • DdcDm
  • Dmel\\CG10697
  • ddc
  • fDDC
  • l(2)37Bl
  • l(2)37Ch
  • l(2)k02104
  • AMD-r
  • CG10501
  • CG17345
  • Dmel\\CG10501
  • X04695
  • fAMD
  • l(2)37Bk
  • l(2)amd
  • l(2)amd alpha-methyldopa hypersensitive
  • l(2)amd[H]
  • Ddc
  • DdcDv
  • Dvir\\GJ17995
  • GJ17995
  • dvir_GLEANR_2561
  • wu:fa56d05
  • wu:fd59h03
  • wu:fk20h01
  • zgc:65801
  • zgc:76929
  • Aadc
  • Dopa decarboxylase
  • alpha methyl dopa-resistant
  • dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • dopa decarboxylase
  • Dopa-decarboxylase
  • Ddc
  • amd
  • DDC
  • ddc
  • Dvir\\Ddc
Alternatives
anti-Cow (Bovine) DDC antibody for Immunohistochemistry
Epitope
AA 32-61, N-Term
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25
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2
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1
Reactivity
Human, Mouse (Murine)
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2
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1
Host
Rabbit
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36
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3
1
Clonality (Clone)
Polyclonal ()
Conjugate
This DDC antibody is un-conjugated
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5
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1
1
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1
1
1
1
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Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
126
60
37
36
35
26
14
13
2
2
1
1
1
1
Options
Supplier
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Immunogen This DDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 AA from the N-terminal region of human DDC.
Clone RB21702
Isotype Ig
Specificity This DDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-69 amino acids from the N-terminal region of human DDC.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DDC (DDC Antibody Abstract)
Background This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.
Synonyms: Aromatic-L-amino-acid decarboxylase,DDC,AADC
Molecular Weight 53894 DA
Gene ID 1644
NCBI Accession NP_000781
UniProt P20711
Pathways Dopaminergic Neurogenesis
Application Notes IF = 1:10-50, WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 32-61), (N-Term) antibody (ABIN651727) DDC Antibody (N-term) (ABIN651727) western blot analysis in mouse liver,kidney tissue...
Immunohistochemistry (IHC) image for anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 32-61), (N-Term) antibody (ABIN651727) DDC Antibody (N-term) (ABIN651727) immunohistochemistry analysis in formalin fixed an...
Flow Cytometry (FACS) image for anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 32-61), (N-Term) antibody (ABIN651727) DDC Antibody (N-term) (ABIN651727) flow cytometric analysis of HepG2 cells (bottom hi...
Background publications Treviño, Yang, French, Hunger, Carroll, Devidas, Willman, Neale, Downing, Raimondi, Pui, Evans, Relling: "Germline genomic variants associated with childhood acute lymphoblastic leukemia." in: Nature genetics, Vol. 41, Issue 9, pp. 1001-5, 2009 (PubMed).

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