MC2R antibody (AA 261-288)

Catalog No. ABIN651731

Product Details anti-MC2R Antibody

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Binding Specificity: AA 261-288

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC2R antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MC2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids of human MC2R.

Clone: RB22805

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MC2R antibody (ABIN651731)

Tetsi Nomigni, Ouzounian, Benoit, Vadrot, Tissier, Renouf, Lefebvre, Christin-Maitre, Louiset: "Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism." in: Endocrine connections, Vol. 4, Issue 2, pp. 117-27, (2015) (PubMed).

Target Details for MC2R

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Alternative Name: MC2R (MC2R Products)

Synonyms: ACTHR antibody, ACTH-R antibody, MC2-R antibody, MC2R antibody, MC2 antibody, melanocortin 2 receptor antibody, MC2R antibody, Mc2r antibody, mc2r antibody

Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands.

Molecular Weight: 33927

Gene ID: 4158

NCBI Accession: NP_000520

UniProt: Q01718

Pathways: cAMP Metabolic Process