SRD5A2 antibody (AA 153-182)

Catalog No. ABIN651742

Product Details anti-SRD5A2 Antibody

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Binding Specificity: AA 153-182

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRD5A2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SRD5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the Central region of human SRD5A2.

Clone: RB26426

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SRD5A2

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Alternative Name: SRD5A2 (SRD5A2 Products)

Synonyms: S5AR 2 antibody, 5ART2 antibody, SRD5alpha2 antibody, SRD5A2 antibody, Srd5a2 antibody, CH73-233A22.6 antibody, wu:fk70d02 antibody, zgc:109942 antibody, zgc:112208 antibody, zgc:112455 antibody, steroid 5 alpha-reductase 2 antibody, steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) antibody, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antibody, steroid-5-alpha-reductase, alpha polypeptide 2a antibody, steroid-5-alpha-reductase, alpha polypeptide 2b antibody, SRD5A2 antibody, Srd5a2 antibody, srd5a2 antibody, LOC100125532 antibody, srd5a2a antibody, srd5a2b antibody

Background: This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

Molecular Weight: 28393

Gene ID: 6716

NCBI Accession: NP_000339

UniProt: P31213

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis